Comparison of susceptibility of Neisseria meningitidis to sodium sulphadiazine and sodium fusidate in vitro.
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چکیده
منابع مشابه
Comparison of susceptibility of Neisseria meningitidis
When prevalence of meningococcal disease is increased contacts of cases may require chemoprophylaxis, and sodium sulphadiazine is the drug of choice. However, increasing numbers of meningococci are resistant to sulphonamides (Fallon, 1975, 1977) andmany alternative chemoprophylactic agents are ineffectual. Sodium fusidate is active against a few strains of meningococci in vitro (Barber and Wate...
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Sir, Reduced susceptibility of Neisseria meningitidis to penicillin (MICs 0.12 mg/L) in the UK was reported by Jones & Sutcliffe in 1990 to be at a level of 3%, comparable to that found in 1987. We have recently undertaken an in vitro study to investigate the susceptibility of meningococci from our collection of strains, to a variety of antimicrobial agents, including penicillin, using BSAC met...
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The microtiter broth dilution method was employed to determine the in vitro susceptibility of 525 recent clinical isolates of anaerobic bacteria to sodium fusidate. The minimal inhibitory concentrations of sodium fusidate ranged from </=0.06 to 1.0 mug/ml for 155 strains of anaerobic gram-positive rods and 130 strains of anaerobic gram-positive cocci. Minimal inhibitory concentrations ranging f...
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Nasopharyngeal isolates of Neisseria meningitidis were tested for growth on nutrient agar with and without the addition of 0.8% sodium chloride. Of the 822 strains tested, 1.3% grew on the salt-free medium, and 74.1% grew on the medium supplemented with sodium chloride.
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Fusidic acid is a bacteriostatic antibiotic that is effective primarily on gram-positive bacteria, such as Staphylococcus and Corynebacterium species. It is often topically applied to the skin, but is also given systemically as a tablet or injection. Allergic contact dermatitis, or urticaria, has been reported as a side effect of fusidic acid treatment, whereas anaphylaxis to topically administ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1978
ISSN: 0021-9746
DOI: 10.1136/jcp.31.4.355